Short-term and Long-term Outcomes Following Laparoscopic Gastrectomy for Advanced Gastric Cancer Compared With Open Gastrectomy
| Autor: | Yosuke Ohno, Nobuki Ichikawa, Shigenori Homma, Tadashi Yoshida, Hideki Kawamura, Kazuaki Shibuya, Masahiro Takahashi, Shusaku Takahashi, Akinobu Taketomi, Hiroyuki Ishizu |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors medicine.medical_treatment Operative Time Risk Assessment Gastroenterology Disease-Free Survival Cohort Studies 03 medical and health sciences 0302 clinical medicine Gastrectomy Stomach Neoplasms Internal medicine medicine Long term outcomes Humans Neoplasm Invasiveness Survival analysis Aged Neoplasm Staging Retrospective Studies Laparotomy D2 lymphadenectomy business.industry Laparoscopic gastrectomy Retrospective cohort study Length of Stay Middle Aged Advanced gastric cancer Survival Analysis Treatment Outcome 030220 oncology & carcinogenesis Lymph Node Excision Female Laparoscopy 030211 gastroenterology & hepatology Surgery Patient Safety business Follow-Up Studies Cohort study |
| Zdroj: | Surgical Laparoscopy, Endoscopy & Percutaneous Techniques. 29:297-303 |
| ISSN: | 1530-4515 |
| Popis: | Introduction To investigate the oncological feasibility and technical safety of laparoscopic gastrectomy with D2 lymphadenectomy for advanced gastric cancer. Methods A total of 186 advanced gastric cancer patients treated by gastrectomy with D2 lymphadenectomy were eligible for inclusion including those with invasion into the muscularis propria, subserosa, and serosa without involvement of other organs, and stages N0-2 and M0. We retrospectively compared the short-term and long-term outcomes between laparoscopic gastrectomy and open gastrectomy. Results We analyzed short-term outcomes by comparing distal with total gastrectomy results. We found no significant difference for distal gastrectomy for postoperative morbidity [laparoscopic vs. open: n=4 (4.6%) vs. n=1 (3.6%); P=1.00]. We also found no significant difference in postoperative morbidity for total gastrectomy [laparoscopic vs. open: n=2 (4.0%) vs. n=1 (4.0%); P=1.00]. No deaths occurred in any group.The entire cohort analysis revealed no statistically significant differences in overall-free or recurrence-free survival between the laparoscopic and open groups. For overall survival, there were no significant differences between open and laparoscopic groups for clinical stage II or III (P=0.29 and 0.27, respectively), and for pathologic stage II or III (P=0.88 and 0.86, respectively). For recurrence-free survival, there were no significant differences between open and laparoscopic groups for clinical stage II or III (P=0.63 and 0.60, respectively), and for pathologic stage II or III (P=0.98 and 0.72, respectively). Conclusion Laparscopic gastrectomy for advanced gastric cancer compared favorably with open gastrectomy regarding short-term and long-term outcomes. |
| Databáze: | OpenAIRE |
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