Physiological background parenchymal uptake of 18F-FDG in normal breast tissues using dedicated breast PET: correlation with mammographic breast composition, menopausal status, and menstrual cycle

Autor: Yuri Shimizu, Hiroko Satake, Satoko Ishigaki, Kazuhiro Shimamoto, Fuga Uota, Masanori Tadokoro, Tomohiro Sato, Katsuhiko Kato, Tsuneo Ishiguchi, Shinji Naganawa
Rok vydání: 2022
Předmět:
Zdroj: Annals of Nuclear Medicine. 36:728-735
ISSN: 1864-6433
0914-7187
Popis: Objective: This study aimed to quantitatively evaluate the effects of age, mammographic density, menopausal status, and menstrual cycle on background parenchymal uptake (BPU) using ring-shaped dedicated breast positron emission tomography (dbPET). Methods: This study included 186 adult women who underwent mammography and dbPET on the same day and had no abnormalities classified as Breast Imaging Reporting and Data System (BI-RADS) category 1 on both examinations. The volume of interest (VOI) was placed in the glandular tissue of both breasts, and the maximum standardized uptake value (SUVmax), mean standardized uptake value (SUVmean), and metabolic breast volume (MBV) were measured as indicators of BPU. We analyzed the correlation between BPU and age, mammographic density, menopausal status, and menstrual cycle. Results: The SUVmax and SUVmean for normal breast tissue were inversely correlated with age (both p
Databáze: OpenAIRE
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