Isolation and nucleotide sequence determination of a gene encoding a heat-stable enterotoxin of Escherichia coli
| Autor: | S L Moseley, Stanley Falkow, P Echeverria, Jonathan Hardy, M I Hug |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
DNA
Bacterial Diarrhea Bacterial Toxins Immunology Enterotoxin Biology medicine.disease_cause Microbiology Enterotoxins Nucleic acid thermodynamics Escherichia coli Homologous chromosome medicine Humans Heat-stable enterotoxin Cloning Molecular Gene Base Sequence Strain (chemistry) Escherichia coli Proteins Nucleic acid sequence Nucleic Acid Hybridization Molecular biology Infectious Diseases Genes Genes Bacterial Parasitology Research Article |
| Zdroj: | Infection and Immunity. 39:1167-1174 |
| ISSN: | 1098-5522 0019-9567 |
| DOI: | 10.1128/iai.39.3.1167-1174.1983 |
| Popis: | A gene encoding a heat-stable enterotoxin (ST) from an Escherichia coli strain isolated from a human with diarrhea was cloned and characterized by nucleotide sequence analysis. The gene was found to be partially homologous to a previously characterized ST gene from an E. coli strain of bovine origin. Hybridization studies showed that most ST-producing strains of E. coli isolated from humans with diarrhea possess genes highly homologous to either the ST gene from the bovine strain or the ST gene characterized in the present study. |
| Databáze: | OpenAIRE |
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