Preoperative leukopenia does not affect outcomes in cancer patients undergoing elective and emergent abdominal surgery: A brief report
| Autor: | Lindy L. Davis, Richard B. Arenas, Jane Garb, Heather M. Grant, Mihaela S. Stefan |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Comorbidity Affect (psychology) Malignancy 03 medical and health sciences 0302 clinical medicine Postoperative Complications Risk Factors Neoplasms medicine Humans Aged Retrospective Studies Chemotherapy Leukopenia business.industry Incidence Confounding Cancer 030208 emergency & critical care medicine Retrospective cohort study General Medicine Middle Aged medicine.disease United States Surgery Survival Rate Elective Surgical Procedures 030220 oncology & carcinogenesis Preoperative Period Female medicine.symptom Emergencies business Abdominal surgery Follow-Up Studies |
| Zdroj: | American journal of surgery. 220(1) |
| ISSN: | 1879-1883 |
| Popis: | Background Leukopenic patients have historically been considered poor surgical candidates due to a perceived increase in operative morbidity and mortality. Methods Retrospective cohort study using the NSQIP database to identify adult patients who received chemotherapy for malignancy within 30-days prior to elective or emergent abdominal surgery between 2008 and 2011. Leukopenia was defined as Results Of the 4369 patients included, 20.2% had preoperative leukopenia. Emergency cases comprised 36.2% of cases. Overall 30-day mortality was 12.2% and 30-day composite morbidity was 29.8%. After controlling for significant confounders, including emergency status, leukopenia was not significantly associated with either postoperative mortality (p = 0.14) or morbidity (p = 0.17). Conclusions Our study suggests that in cancer patients undergoing chemotherapy, leukopenia is not associated with morbidity or mortality and should not influence operative planning in either the elective or emergent setting. |
| Databáze: | OpenAIRE |
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