Detection of norovirus infections in Denmark, 2011–2018
| Autor: | Steen Ethelberg, A Barrasa, L Dam Rasmussen, Thea Kølsen Fischer, E Tvenstrup Jensen, K Dalsgaard Bjerre, M R Korcinska |
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| Rok vydání: | 2020 |
| Předmět: |
Male
0301 basic medicine Epidemiology Denmark medicine.disease_cause Disease Outbreaks 0302 clinical medicine 030212 general & internal medicine Child Caliciviridae Infections Aged 80 and over Surveillance hospital-acquired (nosocomial) infections Middle Aged Infectious Diseases Child Preschool surveillance language Female Seasons Adult medicine.medical_specialty Adolescent 030106 microbiology norovirus Patient identification Danish Young Adult 03 medical and health sciences medicine Humans In patient Aged Original Paper business.industry Norwalk agent and related viruses Public health Norovirus Infant Newborn Infant Outbreak Seasonality medicine.disease language.human_language Hospital-acquired (nosocomial) infections business Demography |
| Zdroj: | Korcinska, M R, Dalsgaard Bjerre, K, Dam Rasmussen, L, Tvenstrup Jensen, E, Kølsen Fischer, T, Barrasa, A & Ethelberg, S 2020, ' Detection of norovirus infections in Denmark, 2011-2018 ', Epidemiology and Infection, vol. 148, e52 . https://doi.org/10.1017/S0950268820000461 Repisalud Instituto de Salud Carlos III (ISCIII) Epidemiology and Infection |
| ISSN: | 1469-4409 0950-2688 |
| Popis: | Norovirus (NoV) infections occur very frequently yet are rarely diagnosed. In Denmark, NoV infections are not under surveillance. We aimed to collect and describe existing laboratory-based NoV data. National NoV laboratory data were collected for 2011–2018, including information on patient identification number, age and sex, requesting physician, analysis date and result. We defined positive patient-episodes by using a 30-day time window and performed descriptive and time series analysis. Diagnostic methods used were assessed through a survey. We identified 15 809 patient-episodes (11%) out of 142 648 tested patients with an increasing trend, 9366 in 2011 vs. 32 260 in 2018. This corresponded with a gradual introduction of polymerase chain reaction analysis in laboratories. The highest positivity rate was in patients aged 85 years (17%). There was a large difference in test performance over five Danish geographical regions and a marked seasonal variation with peaks from December to February. This is the first analysis of national NoV laboratory data in Denmark. A future laboratory-based surveillance system may benefit public health measures by describing trend, burden and severity of seasons and possibly pinpoint hospital outbreaks. |
| Databáze: | OpenAIRE |
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