Supplementary Materials and Methods, Table 1, Figures 1 - 6 from SCP Phosphatases Suppress Renal Cell Carcinoma by Stabilizing PML and Inhibiting mTOR/HIF Signaling

Autor: Ruey-Hwa Chen, Ming-Jer Tang, Xin-Hua Feng, Xia Lin, Xueyan Duan, Hsin-Yi Chen, Li-Ting Lu, Yu-Ching Lin
Rok vydání: 2023
DOI: 10.1158/0008-5472.22403930
Popis: Supplementary Materials and Methods: Description of additional methods used in this study. Supplementary References: List of references cited in Supplementary Materials and Methods. Supplementary Table 1: SCP1 expression in various tumors. Supplementary Figure 1. Screen for PMLS518 phosphatases. Supplementary Figure 2. The specificity of SCP1 antibody. Supplementary Figure 3. Representative IHC staining results for PML, pS518PML, SCP1, SCP3, and KLHL20. Supplementary Figure 4. The effects of combined inhibition of mTOR and PML degradation pathway in suppressing ccRCC. Supplementary Figure 5. The effects of combined treatment on tumor angiogenesis and mice body weight. Supplementary Figure 6. The effect of SCP1 on PML in PC-3 cells.
Databáze: OpenAIRE