Absorbed dose uncertainty estimation for proton therapy
| Autor: | Vesna Spasic-Jokic, A. Dobrosavljević, Petar Belicev |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
therapy
Materials science protons business.industry Nuclear engineering medicine.medical_treatment 3. Good health Metrology Radiation therapy Nuclear Energy and Engineering Absorbed dose Ionization chamber Calibration medicine lcsh:QC770-798 lcsh:Nuclear and particle physics. Atomic energy. Radioactivity absorbed dose Laser beam quality uncertainty Safety Risk Reliability and Quality Nuclear medicine business Proton therapy Beam (structure) |
| Zdroj: | Nuclear technology and radiation protection Nuclear Technology and Radiation Protection, Vol 27, Iss 3, Pp 297-304 (2012) |
| ISSN: | 1452-8185 1451-3994 |
| DOI: | 10.2298/ntrp1203297s |
| Popis: | Successful radiotherapy treatment depends on the absorbed dose evaluation and the possibility to define metrological characteristics of the therapy beam. Radiotherapy requires tumor dose delivery with expanded uncertainty less than ?5 %. It is particularly important to reduce uncertainty during therapy beam calibration as well as to apply all necessary ionization chamber correction factors. Absorbed dose to water was determined using ionometric method. Calibration was performed in reference cobalt beam. Combined standard uncertainty of the calculated absorbed dose to water in 65 MeV proton beam was ?1.97% while the obtained expanded uncertainty of absorbed dose for the same beam quality was ?5.02%. The uncertainty estimation method has been developed within the project TESLA. |
| Databáze: | OpenAIRE |
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