Proteomics of the human pituitary tissue: bioanalytical methods and applications
| Autor: | Sarka Beranova-Giorgianni, Francesco Giorgianni, Diwa Koirala |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Proteomics
Bioanalysis Proteomics methods Proteome Molecular Sequence Data Clinical Biochemistry Computational biology Biology Bioinformatics Mass Spectrometry Analytical Chemistry Humans Electrophoresis Gel Two-Dimensional Amino Acid Sequence General Pharmacology Toxicology and Pharmaceutics Protein Expression Profiling General Medicine Medical Laboratory Technology Post translational Pituitary Gland Protein processing Protein Processing Post-Translational Chromatography Liquid Endocrine gland |
| Zdroj: | Bioanalysis. 6:1989-2003 |
| ISSN: | 1757-6199 1757-6180 |
| DOI: | 10.4155/bio.14.132 |
| Popis: | The pituitary is the central endocrine gland that plays complex regulatory roles in growth, reproduction and metabolism of the body. The human pituitary tissue proteome has been the target of a number of investigations that applied various combinations of advanced separation techniques, mass spectrometry, and bioinformatics tools. This review describes the main features of the bioanalytical workflows used in pituitary proteomics, and summarizes major applications in pituitary proteome mapping, differential protein expression profiling in health and disease, and discovery of post-translational modifications in pituitary proteins. |
| Databáze: | OpenAIRE |
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