Green synthesis and characterization of copper nanoparticles by Tinospora cardifolia to produce nature-friendly copper nano-coated fabric and their antimicrobial evaluation
| Autor: | Vivek Dave, Suman Pant, Kajal Tak, Veera Sadhu, Kakarla Raghava Reddy, Prashansa Sharma |
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| Rok vydání: | 2019 |
| Předmět: |
Microbiology (medical)
Staphylococcus aureus Tinospora Materials science Scanning electron microscope Metal Nanoparticles chemistry.chemical_element Nanoparticle Zinc Microbiology Antioxidants 03 medical and health sciences Escherichia coli Nanobiotechnology Particle Size Fourier transform infrared spectroscopy Molecular Biology 030304 developmental biology 0303 health sciences Plant Extracts 030306 microbiology Textiles Copper Anti-Bacterial Agents chemistry Chemical engineering Transmission electron microscopy Particle size |
| Zdroj: | Journal of Microbiological Methods. 160:107-116 |
| ISSN: | 0167-7012 |
| Popis: | Metallic nanoparticles such as gold, zinc, copper possess anti-microbial activity. These nanoparticles have a small size which provides a large surface area for the interaction with microbes and there are various mechanisms through which copper nanoparticles (CuNPs) act. The demand of these nanoparticles are increasing in the textile industry as they decrease the catalytic degradation property of various dyes as well as being helpful in the treatment of various topical infections. Our aim is to formulate the copper nanoparticle which is capped with Tinospora cardifolia and incorporate these nanoparticles on fabric and to study the anti-microbial activity of these nanoparticles formulated along with their study on the fabric. Formulated nanoparticles were tested for various characterizations such as SEM (Scanning Electron Microscope), TEM (Transmission Electron Microscope) for the microscopical study. The interaction of excipients with the drug was studied using FTIR, XRD, and Raman and the anti-microbial study was studied to determine the activity of the nanoparticles on gram-positive and gram-negative bacteria. Least particle size of 63.3 nm was used as optimized formulation (CuNPs-5) and further used for testing. Laundry durability, ZOI study and %efficacy of copper nanoparticles along with nanoparticle-coated fabric was tested and it was found that fabric was more efficacious for gram-positive bacteria as ZOI for gram positive and gram negative was 21.99 mm and 11 mm. The %efficacy of copper nanoparticle-coated fabric was 101% and 74% at the highest concentration for gram positive and gram negative bacteria respectively. |
| Databáze: | OpenAIRE |
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