Lupane-Type Triterpenes of Phoradendron vernicosum
| Autor: | Sergio R. Peraza-Sánchez, Rosa Moo-Puc, Luis W. Torres-Tapia, Isabel García-Cámara, Lía S. Valencia-Chan |
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| Rok vydání: | 2017 |
| Předmět: |
Plant Components
Phoradendron vernicosum Stereochemistry Pharmaceutical Science 01 natural sciences KB Cells Analytical Chemistry Terpene Normal cell Phoradendron Drug Discovery Humans Mexico Nuclear Magnetic Resonance Biomolecular Pharmacology Molecular Structure 010405 organic chemistry Chemistry Plant Extracts Organic Chemistry Data interpretation Plant Components Aerial Antineoplastic Agents Phytogenic Triterpenes 0104 chemical sciences Plant Leaves 010404 medicinal & biomolecular chemistry Complementary and alternative medicine MCF-7 Cells Molecular Medicine Drug Screening Assays Antitumor Human cancer HeLa Cells |
| Zdroj: | Journal of natural products. 80(11) |
| ISSN: | 1520-6025 |
| Popis: | Three new lupane-type triterpenes, 3α,24-dihydroxylup-20(29)-en-28-oic acid (1), 3α,23-dihydroxy-30-oxolup-20(29)-en-28-oic acid (2), and 3α,23-O-isopropylidenyl-3α,23-dihydroxylup-20(29)-en-28-oic acid (3), together with eight known compounds (4–11) were isolated from a methanol extract of Phoradendron vernicosum aerial parts. The chemical structures of 1–3 were determined on the basis of spectroscopic data interpretation. The isolated compounds were tested against seven human cancer cell lines and two normal cell lines. |
| Databáze: | OpenAIRE |
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