Significant association between Helicobacter pylori infection and serum C-reactive protein
| Autor: | Kentaro Taki, Koji Suzuki, Hisao Ando, Akira Iwase, Toshimitsu Niwa, Shozo Kurotsuchi, Kazuko Nishio, Yoshinori Ito, Nobuyuki Hamajima, Yoshiko Ishida, Kenji Wakai |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: |
Adult
Male medicine.medical_specialty Helicobacter pylori infection Logistic regression Gastroenterology C-reactive protein Body Mass Index Helicobacter Infections Sex Factors Japan Internal medicine medicine Odds Ratio Humans cardiovascular diseases Aged Aged 80 and over biology Helicobacter pylori business.industry Smoking Age Factors nutritional and metabolic diseases General Medicine Odds ratio Middle Aged biology.organism_classification Confidence interval inflammation serum antibody Immunology biology.protein Female Antibody business Body mass index Research Paper |
| Zdroj: | International Journal of Medical Sciences |
| ISSN: | 1449-1907 |
| Popis: | Background: Helicobacter pylori (H. pylori) infection in gastric mucosa may cause systemic inflammatory reaction. This study aimed to examine the association between the infection and serum high sensitivity C-reactive protein (hsCRP). Methods: Subjects were comprised of three groups; 453 health checkup examinees from Yakumo town inhabitants in Hokkaido, Japan (YTI, 153 males and 300 females), 449 health checkup examinees (ENUH, 273 males and 176 females), and 255 female patients of an infertility clinic (PIC), Nagoya University Hospital. Twenty participants with hsCRP more than 1 mg/dl were excluded from the analysis. Those with hsCRP more than 0.1mg/dl were defined as high hsCRP individuals. H. pylori infection status was examined with a serum IgG antibody test. Results: When the three groups were combined, the geometric mean of hsCRP concentration was significantly higher among the seropositives (0.047mg/dl) than among the seronegatives (0.035mg/dl); p |
| Databáze: | OpenAIRE |
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