Phytochemical Composition And Effect Of Aqueous Extract Of Struchium sparganophora (L) On Cockroach Crude Extract – Induced Airway Inflammatory Responses In Wistar Rats

Autor: M E Eko, Eyong U. Eyong, Mbeh U. Eteng
Jazyk: angličtina
Rok vydání: 2008
Předmět:
Zdroj: Global Journal of Pure and Applied Sciences; Vol 14, No 4 (2008); 417-422
ISSN: 1118-0579
Popis: Asthma, a chronic immune inflammatory disorder of the airways has been responsible for high mortality in both infants and adults in Africa and appropriate therapy has long been sought. Phytochemical composition and effect of aqueous extract of Struchium sparganophora on pulmonary inflammation induced in Wistar rat asthma model were studied. Pulmonary inflammation was induced in Wistar rats against appropriate controls with cockroach (Periplaneta americana) crude extract. Twenty-four hours after asthma induction treatment, S. spargonophora extract was administered by oral gavage to induced rats. The inflammatory responses and effect of the extract were assessed by analysis of leukocytes infiltration in bronchoalveolar lavage fluid at 12 hourly intervals. The aqueous extract of S. sparganophora contained alkaloids, flavonoids, steroids, glycosides, polyphenols, saponins, tannins etc. The aqueous extract significantly (p Keywords : Phytochemical, S. sparganophora (L), inflammation, rats, asthma. Global Journal or Pure and Applied Sciences Vol. 14 (4) 2008: pp. 417-122
Databáze: OpenAIRE