Autor: |
Sharon J. Peacock, Gladys Tan, Rebecca Lipsitz, Ivo Steinmetz, Direk Limmathurotsakul, Allen C. Cheng, Nicki Pesik, Jay E. Gee, David A. B. Dance, Susan Garges, Bart J. Currie, Patrick Tan, Elizabeth O’Mara, David D. Blaney, Meredith G. Morrow, L. Paige Rogers, W. Joost Wiersinga, Herbert P. Schweizer, Vanaporn Wuthiekanun, Rosemarie Aurigemma, Joseph Larsen, Robert Norton, Theresa L. Smith, Prasith Baccam |
Přispěvatelé: |
AII - Amsterdam institute for Infection and Immunity, Infectious diseases |
Jazyk: |
angličtina |
Rok vydání: |
2012 |
Předmět: |
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Zdroj: |
Emerging infectious diseases, 18(12). Centers for Disease Control and Prevention (CDC) Emerging Infectious Diseases Emerging Infectious Diseases, Vol 18, Iss 12, Pp-(2012) |
ISSN: |
1080-6040 |
Popis: |
The US Public Health Emergency Medical Countermeasures Enterprise convened subject matter experts at the 2010 HHS Burkholderia Workshop to develop consensus recommendations for postexposure prophylaxis against and treatment for Burkholderia pseudomallei and B. mallei infections, which cause melioidosis and glanders, respectively. Drugs recommended by consensus of the participants are ceftazidime or meropenem for initial intensive therapy, and trimethoprim/sulfamethoxazole or amoxicillin/clavulanic acid for eradication therapy. For postexposure prophylaxis, recommended drugs are trimethoprim/sulfamethoxazole or co-amoxiclav. To improve the timely diagnosis of melioidosis and glanders, further development and wide distribution of rapid diagnostic assays were also recommended. Standardized animal models and B. pseudomallei strains are needed for further development of therapeutic options. Training for laboratory technicians and physicians would facilitate better diagnosis and treatment options. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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