Angiographic Studies of the Totally Arterialized Rat Liver
| Autor: | Torsten Holmin, K. Ivancev, J. Teuscher, G. Flati, B. Buchholtz |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
Male
medicine.medical_specialty Cirrhosis Left gastric artery Fistula Portacaval shunt Hepatic Artery medicine.artery medicine Animals Arterioportal fistula Radiology Nuclear Medicine and imaging In patient Portacaval Shunt Surgical Portal Vein business.industry Stomach Angiography General Medicine medicine.disease Rats Surgery Liver Rat liver Arteriovenous Fistula Blood supply business |
| Zdroj: | Investigative Radiology. 18:436-440 |
| ISSN: | 0020-9996 |
| DOI: | 10.1097/00004424-198309000-00006 |
| Popis: | Twenty-three angiographies were performed in 20 rats with a totally arterialized liver. The arterialization was obtained by the construction of an end-to-side portacaval shunt (PCS) and an arteriovenous (AV) fistula between the left gastric artery and the portal stump. Microsurgical technique was necessary because of the small diameter of the AV fistula (0.5 mm). The angiographic examinations showed an AV fistula patency rate of 70% and a PCS rate of 100%. A successively increasing diameter of the fistula with dilation of the intrahepatic portal vessels was demonstrated in the rats with a patent arterioportal fistula. Tortuous and irregular vessels were also observed. All these signs suggest an overarterialization which developed despite the use of a very small AV fistula. None of the three rats examined histologically had cirrhosis of the liver. Further research is needed to attempt to avoid or minimize the deleterious effects of overarterialization of the portal tree, while utilizing the advantages of a dual liver blood supply in patients with decompressive PCS. |
| Databáze: | OpenAIRE |
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