First Molecular Identifications of Necator americanus and Ancylostoma ceylanicum Infecting Rural Communities in Lower Myanmar
| Autor: | Jurairat Jongthawin, Thi Thi Htoon, Rutchanee Ropai, Lakkhana Sadaow, Oranuch Sanpool, Wanchai Maleewong, Win Pa Pa Aung, Pewpan M. Intapan, Htay Htay Tin, Issarapong Phosuk |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Rural Population
0301 basic medicine Ancylostoma Necator americanus education 030231 tropical medicine Helminth genetics Myanmar Polymerase Chain Reaction law.invention Necatoriasis Feces 03 medical and health sciences 0302 clinical medicine Species Specificity law Zoonoses Virology parasitic diseases medicine Animals Humans Parasite hosting Internal transcribed spacer Polymerase chain reaction Ancylostoma ceylanicum biology Zoonosis Articles DNA Helminth 030108 mycology & parasitology biology.organism_classification medicine.disease Infectious Diseases Hookworm Infections Parasitology |
| Zdroj: | The American Journal of Tropical Medicine and Hygiene. 96:214-216 |
| ISSN: | 1476-1645 0002-9637 |
| DOI: | 10.4269/ajtmh.16-0610 |
| Popis: | Hookworms are enteric parasitic roundworms infecting an estimated 400 million persons worldwide. Herein, we provide the first molecular identifications of human hookworms from certain parts of rural Lower Myanmar. DNA was extracted from hookworm-positive stool samples, as determined by microscopy. DNA sequences of the partial internal transcribed spacer 1, full length 5.8S gene, and partial internal transcribed spacer 2 were determined and compared with available hookworm sequences from public databases. Of the 11 polymerase chain reaction–positive samples, eight (Bago Region, N = 4; Mon State, N = 4) yielded sequences with high similarity to those of Necator americanus. A further three sequences (Mon State, N = 2; Bago Region, N = 1) showed high similarity with those of Ancylostoma ceylanicum. The latter is primarily a parasite of dogs and represents a zoonosis. Given that different species of hookworms exhibit different epidemiological and biological characteristics, accurate identification is essential for the planning and execution of effective control programs for hookworm infections. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|