Is the rabbit ear model, in its present state, prophetic of acnegenicity?

Autor:	Samuel B. Frank
Rok vydání:	1982
Předmět:	Adult Keratitis medicine.medical_specialty Myristates Petrolatum business.industry Rabbit (nuclear engineering) Ear Dermatology Cosmetics Surgery Disease Models Animal Acne Vulgaris medicine Animals Humans Mineral Oil Female Rabbits Pharmaceutical Vehicles business Sulfur Skin
Zdroj:	Journal of the American Academy of Dermatology. 6(3)
ISSN:	0190-9622
Popis:	The rabbit ear model has been proposed as a useful bioassay to establish the comedogenic and acnegenic qualities of chemical compounds and finished products, pharmaceutical and cosmetic, for topical application. This review highlights the many problems in performance of the test method, the absence of correlation with experience in the human, and, consequently, the serious limitations to the conclusions that can reasonably be drawn, especially for the clinical dermatologist.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b067f388818edd549375dbfd42a8d60 https://pubmed.ncbi.nlm.nih.gov/6461674 Zobrazit plný text záznamu