Catechin, rutin and quercetin in Quercus mongolica Fisch leaves exert inhibitory effects on multiple cancer cells

Autor:	Linmei Wang, Xingfan Du, Dongmei Yue, Xinghe Chen
Rok vydání:	2022
Předmět:	Pharmacology Biophysics Cell Biology Food Science
Zdroj:	Journal of Food Biochemistry. 46
ISSN:	1745-4514 0145-8884
DOI:	10.1111/jfbc.14486
Popis:	We aimed to identify anti-tumor agents in Quercus mongolica Fisch (QMF). Bioactive compounds in QMF leaves, which were extracted using ethanol as a co-solvent. Five point zero six grams of flavonoids were obtained from 100 g of QMF leaves. Catechin (18.4%), rutin (6.3%), ellagic acid (34.9%), quercetin (5.1%) and kaempferol (20.6%) are the main ingredients of the extracts and were further purified by HPLC. CCK-8 cell proliferation assay showed that catechin and ellagic acid exerted strong inhibitory effects on the proliferation of all cancer cells with lower IC
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af6c8eecac0d92a7ce9bf437aa5c105 https://doi.org/10.1111/jfbc.14486 Zobrazit plný text záznamu