Changing patterns of disseminated gonococcal infection in France: cross-sectional data 2009–2011: Table 1
| Autor: | Régis Goursaud, Benoit Cazenave, Vincent Jarlier, O. Patey, Sophie Dellion, Jocelyne Ouanich, J. Breuil, Flore Lacassin, Eric Caumes, Anna Belkacem |
|---|---|
| Přispěvatelé: | Centre Hospitalier Intercommunal de Villeneuve-Saint-Georges (CHIV), Service des maladies infectieuses et tropicales [CHU Pitié-Salpêtrière], CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Centre d'Immunologie et de Maladies Infectieuses (CIMI), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC), Service de Médecine interne, Centre Hospitalier Territorial de Noumea, Service de Médecine Interne, Maladies Infectieuses et Tropicales [Villeneuve-Saint-Georges], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS) |
| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
[SDV]Life Sciences [q-bio] Prostatitis Dermatology medicine.disease_cause 03 medical and health sciences 0302 clinical medicine [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases Internal medicine Pelvic inflammatory disease Epidemiology Medicine Endocarditis Sex organ 030212 general & internal medicine ComputingMilieux_MISCELLANEOUS 0303 health sciences Tenosynovitis 030306 microbiology business.industry medicine.disease 3. Good health Surgery Infectious Diseases Ceftriaxone Neisseria gonorrhoeae business [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology medicine.drug |
| Zdroj: | Sexually Transmitted Infections Sexually Transmitted Infections, BMJ Publishing Group, 2013, 89 (8), pp.613-615. ⟨10.1136/sextrans-2013-051119⟩ Sexually Transmitted Infections, 2013, 89 (8), pp.613-615. ⟨10.1136/sextrans-2013-051119⟩ |
| ISSN: | 1472-3263 1368-4973 |
| DOI: | 10.1136/sextrans-2013-051119 |
| Popis: | Objectives Disseminated gonococcal infections (DGIs) are rare. We describe the characteristics of DGIs in France. Methods This is a 3-year retrospective analysis of DGI cases collected through two networks of microbiologists and infectious disease specialists in France between 2009 and 2011. DGI was defined either by the isolation of Neisseria gonorrhoeae from blood and synovial fluid or by the existence of a clinical syndrome consistent with DGI and the isolation of N gonorrhoeae from any site. We describe the epidemiological, clinical and microbiological characteristics and outcomes of DGIs. Results 21 patients (9 women, 12 men; 18–62 years old) were diagnosed with DGI. The number of DGI cases increased between 2009 and 2011. Two men who had sex with men were coinfected with HIV. We found 28 extragenital locations, including arthritis (14 cases), tenosynovitis (7), skin lesions (4), endocarditis (1), prostatitis (1) and pelvic inflammatory disease (1). Genital signs were present in five patients. The diagnosis was confirmed by cultures in 20 patients—blood (4), synovial fluid (11), genital (3), throat (1), urine (1)—and by molecular biology on a pharyngeal swab in 1 patient. Seven cases were resistant to fluoroquinolones. The patients were treated with ceftriaxone, associated with corticosteroids (two cases) and surgery (six cases). Four patients had joint sequelae. Conclusions DGIs are increasing. Men seem to be at higher risk than women. Joint involvement was common. Microbiological diagnosis was based on culture, however molecular biology using pharyngeal swabs was helpful when cultures were negative. |
| Databáze: | OpenAIRE |
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