Transgenerational effects of insecticides - implications for rapid pest evolution in agroecosystems
| Autor: | Leena Lindström, Kristian Brevik, Stephanie D. McKay, Yolanda H. Chen |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Integrated pest management Insecticides Insecta pest evolution agroecosystems Context (language use) Biology insektisidit Epigenesis Genetic Insecticide Resistance 03 medical and health sciences Animals Epigenetics Ecology Evolution Behavior and Systematics Epigenesis Resistance (ecology) fungi food and beverages Pesticide hyönteismyrkyt Biological Evolution Crop Production tuholaistorjunta 030104 developmental biology Histone Evolutionary biology Insect Science DNA methylation biology.protein hyönteiset ta1181 agroekologia torjuntamenetelmät |
| Popis: | Although pesticides are a major selective force in driving the evolution of insect pests, the evolutionary processes that give rise to insecticide resistance remain poorly understood. Insecticide resistance has been widely observed to increase with frequent and intense insecticide exposure, but can be lost following the relaxation of insecticide use. One possible but rarely explored explanation is that insecticide resistance may be associated with epigenetic modifications, which influence the patterning of gene expression without changing underlying DNA sequence. Epigenetic modifications such as DNA methylation, histone modifications, and small RNAs have been observed to be heritable in arthropods, but their role in the context of rapid evolution of insecticide resistance remain poorly understood. Here, we discuss evidence supporting how: firstly, insecticide-induced effects can be transgenerationally inherited; secondly, epigenetic modifications are heritable; and thirdly, epigenetic modifications are responsive to pesticide and xenobiotic stress. Therefore, pesticides may drive the evolution of resistance via epigenetic processes. Moreover, insect pests primed by pesticides may be more tolerant of other stress, further enhancing their success in adapting to agroecosystems. Resolving the role of epigenetic modifications in the rapid evolution of insect pests has the potential to lead to new approaches for integrated pest management as well as improve our understanding of how anthropogenic stress may drive the evolution of insect pests. peerReviewed |
| Databáze: | OpenAIRE |
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