tert-Butyl nitrite promoted transamidation of secondary amides under metal and catalyst free conditions
| Autor: | Popuri Sureshbabu, Priyanka Chaudhary, Sadaf Azeez, Jeyakumar Kandasamy |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Tert butyl
Primary (chemistry) 010405 organic chemistry Chemistry Organic Chemistry 010402 general chemistry 01 natural sciences Biochemistry 0104 chemical sciences Catalysis Metal chemistry.chemical_compound visual_art visual_art.visual_art_medium Organic chemistry Physical and Theoretical Chemistry Nitrite |
| Zdroj: | Organic & Biomolecular Chemistry. 17:845-850 |
| ISSN: | 1477-0539 1477-0520 |
| DOI: | 10.1039/c8ob03010c |
| Popis: | A mild and efficient method is demonstrated for the transamidation of secondary amides with various amines including primary, secondary, cyclic and acyclic amines in the presence of tert-butyl nitrite. The reaction proceeds through the N-nitrosamide intermediate and provides the transamidation products in good to excellent yields at room temperature. Moreover, the developed methodology does not require any catalyst or additives. |
| Databáze: | OpenAIRE |
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