Analysis of the interrelation between immune factors and inflammatory markers, and the course of chronic heart failiure in patients with rheumathoid arthritis

Autor: A S Ankudinov, A. N. Kalyagin
Rok vydání: 2018
Předmět:
Zdroj: Alexey Kalyagin
Scopus-Elsevier
ISSN: 0022-9040
DOI: 10.18087/cardio.2495
Popis: This review presents relevant information about development and course of chronic heart failure (CHF) associated with rheumatoid arthritis (RA). One of the most discussed issues is the effect of systemic inflammatory process on prognosis of CHF. The review focused on current evidence for significance of this comorbidity in CHF. The diagnostic role of current immune markers, such as galectin 3, pentraxin 3, growth differentiation factor 15, and osteopontin was described. The review discussed the significance of antiinflammatory therapy for prognosis of CHF in the presence of systemic diseases. Possible beneficial effects of the basis therapy for RA on CHF outcomes were assessed. The authors noted a positive prognostic significance of methotrexate for the risk of decompensated CHF.
Databáze: OpenAIRE