Comparison of two surgical approaches for treating vitiligo: a preliminary study
| Autor: | Binnur Tüzün, Oguz Cetinkale, Cem Mat, Yalçın Tüzün, Ronni Wolf, Mustafa Özdemir, Agop Kotoğyan |
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| Rok vydání: | 2002 |
| Předmět: |
Adult
medicine.medical_specialty Suction Adolescent Vitiligo Skin Pigmentation Dermatology Surgical methods Vacuum extractor Blister Double-Blind Method medicine Gluteal region Humans Child skin and connective tissue diseases Surgical approach integumentary system business.industry Blisters Skin Transplantation Middle Aged medicine.disease Suction blister Surgery Treatment Outcome medicine.symptom business |
| Zdroj: | International Journal of Dermatology. 41:135-138 |
| ISSN: | 1365-4632 0011-9059 |
| DOI: | 10.1046/j.1365-4362.2002.01391.x |
| Popis: | Background Surgical techniques have recently been introduced for patients with vitiligo. Randomized controlled trials have not been performed. Aim To compare the efficacy and side-effects of two surgical methods (suction blister vs. thin split-thickness graft technique) for the treatment of vitiligo. Methods Three suction blisters, approximately 0.8 cm in diameter, made with a special tool attached to a vacuum extractor, which were converted to erosions by removal of the roofs of the bullae, and one round erosion of approximately the same diameter, made using a silver knife, were created. One roof of a blister and two cutaneous thin split-thickness grafts taken from the gluteal region were transferred onto recipient vitiliginous areas; one was left alone. The results were evaluated by one non-blind and two blind observers bimonthly during the 3-month follow-up period. Results Repigmentation rates were 25-65% in the suction blister technique and 90% in the thin split-thickness graft technique (P < 0.001). Conclusions The thin split-thickness graft technique is superior to the suction blister technique in treating vitiligo. |
| Databáze: | OpenAIRE |
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