Effects of ethanol and methanol on lipid metabolism in Bacillus subtilis
| Autor: | Jean-Pierre Bohin, Bernard Lubochinsky, Daniel Rigomier |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
chemistry.chemical_classification
Phosphatidylethanolamine Phosphatidylglycerol Ethanol Methanol Fatty Acids Fatty acid Lipid metabolism Phosphatidylglycerols Bacillus subtilis Biology biology.organism_classification Lipid Metabolism Microbiology chemistry.chemical_compound chemistry Biochemistry Bacteria Phospholipids |
| Zdroj: | Journal of general microbiology. 121(1) |
| ISSN: | 0022-1287 |
| Popis: | In Bacillus subtilis, the fatty acid moiety of the phospholipids was affected differently during growth in the presence of 1.1 M-methanol or 0.7 M-ethanol, though at these concentrations methanol and ethanol had the same effects on growth rate and completely inhibited sporulation. Synthesis of phosphatidylglycerol was also strongly inhibited and the amount of total cell phospholipids was reduced by 50% by both alcohols. The composition of fatty acids, especially the relative concentration of 12-methyltetradecanoic acid, was modified only by ethanol; in bacteria grown in the presence of methanol, changes in fatty acid composition were negligible. In non-sporulating mutants, synthesis of phosphatidylglycerol was much less affected than in the wild-type and synthesis of phosphatidylethanolamine was increased. In these strains, fatty acid composition was also modified by ethanol but unaffected by methanol. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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