Fos Expression in the Brainstem Nuclei Evoked by Nasal Air-Jet Stimulation in Rats
| Autor: | Yasuaki Harabuchi, Masaaki Adachi, Takuya Arakawa, Akihiro Katada, Satoshi Nonaka, Isamu Kunibe |
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| Rok vydání: | 2007 |
| Předmět: |
Male
Nasal cavity medicine.medical_specialty Gene Expression Mucous membrane of nose Stimulation Rats Sprague-Dawley Physical Stimulation Internal medicine Solitary Nucleus medicine Animals Medulla business.industry Air Solitary nucleus Spinal trigeminal nucleus Solitary tract Genes fos Rats medicine.anatomical_structure Endocrinology Otorhinolaryngology Parvocellular reticular nucleus Female Nasal Cavity business |
| Zdroj: | American Journal of Rhinology. 21:128-132 |
| ISSN: | 1539-6290 1050-6586 |
| DOI: | 10.2500/ajr.2007.21.2910 |
| Popis: | Background Noxious stimulation of the nasal mucosa may induce protective reflexes in the upper airway in rats. Previously, we have reported that nasal air-jet stimulation increases the activities of the laryngeal muscles in decerebrate cats; however, the neuronal mechanism of this phenomenon still is not clarified. Methods After the application of nasal air-jet stimulation for 2 hours, we investigated the distribution of Fos-positive cells (FPCs) throughout the medulla compared with sham-operated rats using Fos immunoreactivity. Results FPCs in the spinal trigeminal nucleus, the parvocellular reticular nucleus, and the nucleus of the solitary tract were more frequent than the sham-operated rats. Conclusion These results suggest that the afferents induced by air-jet stimulation were conveyed to these FPCs and that some of these cells might participate in the augmentation of laryngeal muscle activities during nasal air-jet stimulation. |
| Databáze: | OpenAIRE |
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