Neuroimaging and Correlates of Cognitive Function among Patients with Heart Failure
| Autor: | Henry C. Weinstein, Raymond L.C. Vogels, Jutta M. Schroeder-Tanka, Philip Scheltens, Joukje M. Oosterman, Barbera van Harten, Wiesje M. van der Flier, Alida A. Gouw |
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| Přispěvatelé: | Neurology |
| Rok vydání: | 2007 |
| Předmět: |
Male
medicine.medical_specialty Health Status Cognitive Neuroscience Myocardial Ischemia Neuropsychological Tests Severity of Illness Index Internal medicine Prevalence medicine Humans Effects of sleep deprivation on cognitive performance Neuropsychological assessment Psychiatry Aged Heart Failure Mini–Mental State Examination medicine.diagnostic_test Cognitive disorder Brain Cognition Middle Aged medicine.disease Executive functions Magnetic Resonance Imaging Hyperintensity Psychiatry and Mental health Cardiology Female Geriatrics and Gerontology Cognition Disorders Psychology Executive dysfunction |
| Zdroj: | Vogels, R L C, Oosterman, J M, Van Harten, B, Gouw, A A, Schroeder-Tanka, J M, Scheltens, P, Van Der Flier, W M & Weinstein, H C 2007, ' Neuroimaging and correlates of cognitive function among patients with heart failure ', Dementia and Geriatric Cognitive Disorders, vol. 24, no. 6, pp. 418-423 . https://doi.org/10.1159/000109811 Dementia and Geriatric Cognitive Disorders, 24(6), 418-423. S. Karger AG |
| ISSN: | 1421-9824 1420-8008 |
| DOI: | 10.1159/000109811 |
| Popis: | Background/Aims: We purposed to investigate the relationship between cerebral abnormalities detected by magnetic resonance imaging (MRI) and cognitive performance in nondemented outpatients with heart failure (HF). Methods: In 58 patients with HF neuropsychological assessment was performed including tests of mental speed, executive functions, memory, language and visuospatial functions. Deep, periventricular and total white matter hyperintensities (WMH), lacunar and cortical infarcts, global and medial temporal lobe atrophy (MTA) were investigated on MRI of the brain. Correlations between MRI findings and the cognitive measures were calculated. Results: MTA correlated with memory (r = –0.353, p < 0.01), with executive functions (r = –0.383, p < 0.01) and the Mini Mental State Examination (r = –0.343, p < 0.05). Total WMH and deep WMH were found to correlate with depression and anxiety scores, but not with cognitive measures. Age, estimated premorbid intelligence and MTA were independent predictors of diminished cognitive performance. Conclusions: In HF patients, MTA was related to cognitive dysfunction, involving memory impairment and executive dysfunction, whereas WMH was related to depression and anxiety. |
| Databáze: | OpenAIRE |
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