Relation between serum uric acid levels with the degree of coronary artery disease: A prospective study from Ecuador
| Autor: | Hans Mautong, Geovanny Efraín Alvarado-Villa, Xavier Wong-Achi, Maria Egas-Izquierdo |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Coronary angiography medicine.medical_specialty Prior diagnosis Coronary Artery Disease 030204 cardiovascular system & hematology Coronary Angiography Severity of Illness Index Coronary artery disease 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Internal medicine Humans Medicine Pharmacology (medical) Prospective Studies 030212 general & internal medicine Prospective cohort study Aged General Environmental Science business.industry Serum uric acid General Engineering Middle Aged medicine.disease Uric Acid Regional hospital Cross-Sectional Studies chemistry Hypertension General Earth and Planetary Sciences Uric acid Female Observational study Ecuador Cardiology and Cardiovascular Medicine business |
| Zdroj: | Clínica e Investigación en Arteriosclerosis. 31:8-14 |
| ISSN: | 0214-9168 |
| Popis: | To analyze the relationship between serum levels of uric acid and the severity of coronary disease.This observational, descriptive and cross-sectional study included 77 patients previously selected using inclusion criteria, from September 2014 to May 2015. It was conducted in a third level regional hospital from Guayaquil, Ecuador. Patients enrolled in this study were older than 30 years with coronary disease undergoing coronary angiography, without prior diagnosis of any other condition that could influence in serum uric acid values.(1) Direct relation between serum uric acid levels and the severity of coronary disease, with a 0.600 Spearman correlation coefficient (p0.001); (2) other variables such as hypertension and medical history did not have an influence on the study's results; (3) serum uric acid levels didn't show difference among the different groups (p˃0.05).Based on the results, it was possible to conclude that there is a relation between serum uric acid level and the severity of coronary artery disease; this relation was independent of clinical diagnosis and hypertension. According to this, serum uric acid levels can be taken as a practical and inexpensive parameter related to the severity of coronary artery disease. As a primary preventive intervention, we recommend maintaining levels within normal parameters in patients with cardiovascular risk. |
| Databáze: | OpenAIRE |
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