The vaccination and challenge with bovine viral diarrhea virus (BVDV) of calves previously infected with a non-cytopathic BVDV
| Autor: | F Frigeri, Maura Ferrari, G Castrucci, V. Traldi |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
viruses
Immunology Observation period Fluorescent Antibody Technique Bovine viral diarrhea virus BVDV Antibodies Viral Vaccines Attenuated Microbiology Virus Infectious bovine rhinotracheitis virus Neutralization Tests Animals Immunology and Allergy Viral diarrhea Cells Cultured Diarrhea Viruses Bovine Viral General Veterinary biology Pestivirus Viral Vaccines General Medicine biology.organism_classification Virology Vaccination Infectious Diseases Togaviridae Bovine Virus Diarrhea-Mucosal Disease Cattle |
| Zdroj: | Comparative Immunology, Microbiology and Infectious Diseases. 14:31-38 |
| ISSN: | 0147-9571 |
| DOI: | 10.1016/0147-9571(91)90038-f |
| Popis: | Four calves were infected with noncytopathic (NCP) New York-1 strain of bovine viral diarrhea virus (BVDV). During the observation period of one month the calves remained clinically normal but the virus was repeatedly recovered from their pharyngeal swabbings and blood. Thirty days following infection the four calves were vaccinated, together with two uninfected calves, with a modified-live vaccine containing cytopathic (CP) BVDV, infectious bovine rhinotracheitis virus and parainfluenza-3 virus. No detrimental effects were observed after vaccination. Forty-three days after vaccination the calves were challenged by exposure either with the CP TVM-2 strain or the NCP New York-1 strain of BVDV. The vaccinated calves remained healthy throughout the 60-day observation period. |
| Databáze: | OpenAIRE |
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