Validity of laser speckle contrast imaging for the prediction of burn wound healing potential
| Autor: | Matthea M. Stoop, Anouk Pijpe, K.J. Zheng, P.P.M. van Zuijlen, Esther Middelkoop |
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| Přispěvatelé: | Plastic, Reconstructive and Hand Surgery, AMS - Tissue Function & Regeneration, Paediatric Surgery |
| Rok vydání: | 2022 |
| Předmět: |
Adult
Laser Doppler Imaging Critical Care and Intensive Care Medicine Contrast imaging Validity Healing potential 030207 dermatology & venereal diseases 03 medical and health sciences Speckle pattern 0302 clinical medicine Diagnostic measurement tools Laser-Doppler Flowmetry Humans Medicine Prospective Studies Child Reference standards Skin Wound Healing Burn wound Receiver operating characteristic business.industry 030208 emergency & critical care medicine General Medicine Laser Speckle Contrast Imaging Patient population Emergency Medicine Surgery Burns Nuclear medicine business Total body surface area |
| Zdroj: | Zheng, K J, Middelkoop, E, Stoop, M, van Zuijlen, P P M & Pijpe, A 2021, ' Validity of laser speckle contrast imaging for the prediction of burn wound healing potential ', Burns . https://doi.org/10.1016/j.burns.2021.04.028 Burns. Elsevier Limited |
| ISSN: | 0305-4179 |
| DOI: | 10.1016/j.burns.2021.04.028 |
| Popis: | Objective: To assess validity of Laser Speckle Contrast Imaging (LSCI) for the measurement of burn wound healing potential (HP) in a burn centre patient population, based on Laser Doppler Imaging (LDI) as reference standard. Method: A single-centre prospective observational cohort study was performed between September–December 2019. A total of 50 burns in 14 patients were included. Imaging and data collection were standardized. Correlation between LSCI and LDI flux values was tested. ROC curves were developed to test the discriminative ability of LSCI between LDI HP categories. Results: Number of adults and children were equal. Mean total body surface area burnt was 5.5%. Main burn causes were scalds (64%) and flame burns (36%). LSCI set-up and imaging duration was 3 min and 10 s, respectively. LSCI was able to discriminate between wounds with early versus delayed HP (21 days, similar sensitivity (74%) and specificity (95%) were found (p < 0.001). Correlations between LSCI and LDI flux values were moderate (21 days). Conclusion: LSCI shows good validity for the prediction of burn wound HP. It is a highly feasible, patient and physician friendly tool. |
| Databáze: | OpenAIRE |
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