A Green Chemistry Method for the Regeneration of Carbonyl Compounds from Oximes by Using Cupric Chloride Dihydrate as a Recoverable Promoter for Hydrolysis

Autor:	Rui-Heng Zhu, Liang-Deng Nie, Jing Dong, Na Quan, Xiao-Xin Shi
Rok vydání:	2011
Předmět:	Reaction conditions Solvent Green chemistry Hydrolysis chemistry.chemical_compound Cupric salt Chemistry Yield (chemistry) Organic Chemistry Cupric chloride dihydrate Organic chemistry Oxime Nuclear chemistry
Zdroj:	Synlett. 2011:1028-1032
ISSN:	1437-2096 0936-5214
DOI:	10.1055/s-0030-1259730
Popis:	A mild, efficient, general, and green method for the regenerationof carbonyl compounds from their corresponding oximes is described.Cupric salts promoted hydrolysis of oximes was studied, and thebest reaction conditions for the hydrolysis have been found. Carbonylcompounds were obtained in 85-98% yields afterthe treatment of oximes with 2 molar equivalent of CuCl 2 ˙2H 2 Oat reflux (around 75 ˚C) in a mixed solvent ofacetonitrile and water (4:1). In addition, cupric salt was readilyrecovered in an almost quantitative yield via the complete precipitationof Cu(OH) 2 ˙2H 2 O.
Databáze:	OpenAIRE
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