Effects of the treatment with acarbose in elderly overweight type 2 diabetic patients in poor glycemic control with oral hypoglycemic agents or insulin
| Autor: | T. Attardo, L. Sangiorgio, Michele Lunetta, L. Condorelli |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Aging
Meal medicine.medical_specialty Health (social science) business.industry Insulin medicine.medical_treatment Type 2 diabetes Overweight medicine.disease Gastroenterology Endocrinology Postprandial Metabolic control analysis Internal medicine medicine Geriatrics and Gerontology medicine.symptom business Gerontology Glycemic Acarbose medicine.drug |
| Zdroj: | Archives of Gerontology and Geriatrics. 31:27-34 |
| ISSN: | 0167-4943 |
| DOI: | 10.1016/s0167-4943(00)00064-9 |
| Popis: | The aim of this study was to evaluate the efficacy of acarbose, an inhibitor of alpha-glucosidase, on glycemic control in elderly overweight type 2 diabetic patients poorly controlled by oral hypoglycemic agents (OHA) or insulin. Our study included 22 overweight patients, 60-75-years-old, treated with OHA and/or insulin who, after a period of 4 weeks of controlled diet, showed a poor metabolic control. They were divided into two groups: Group I (nine patients) on OHA treatment; Group II (13 patients) undergoing treatment with insulin alone or in combination with OHA. Acarbose was administered to all the patients (100 mg three times a day at meal times) for 6 months in addition to their previous treatment. The addition of acarbose caused a significant reduction in both groups with regard to fasting glycemia (after 3 and 6 months, respectively, 20.7 and 21.9%, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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