DNA methylation: A transcriptional mechanism co-opted by the developed mammalian brain?
| Autor: | Courtney A. Miller, Mikael A. Mikaelsson |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Genetics
Regulation of gene expression Cancer Research Transcription Genetic Mechanism (biology) Long-Term Potentiation Brain Gene Expression Regulation Developmental Computational biology Genetics Behavioral Biology DNA Methylation Mammalian brain Epigenesis Genetic Epigenetics of physical exercise Gene Expression Regulation Memory DNA methylation Transcriptional regulation Animals Epigenetics Point-of-View Molecular Biology DNA Modification Methylases Epigenomics |
| Popis: | Forming and maintaining behavioral memories is a complex process that involves, among other requirements, transcriptional regulation and systems communication. Here we review recent studies exploring the role of DNA methylation in these critical processes. Further, we suggest that, perhaps, the adult brain controls and utilizes the mechanism of DNA methylation in non-traditional ways that are waiting to be explored. |
| Databáze: | OpenAIRE |
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