Comparison of characteristics and biocompatibility of green synthesized iron oxide nanoparticles with chemical synthesized nanoparticles
| Autor: | Woo Jin Chung, Shazia Anjum Musthafa, Aarrthy M. Arunachalam, Murugesan Chandrasekaran, Kantha Deivi Arunachalam, Balasubramani Ravindran, Ganesh Munuswamy Ramanujam, Sunita Varjani, S.B. Mohamed Khalith, Soon Woong Chang, Sathish Kumar Karuppannan, Mohammed Junaid Hussain Dowlath |
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| Rok vydání: | 2021 |
| Předmět: |
Biocompatibility
Metal Nanoparticles Nanoparticle Biocompatible Materials Green Chemistry Technology Nanotechnology 010501 environmental sciences Biocompatible material 01 natural sciences Biochemistry 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Bioremediation chemistry Drug delivery Magnetic Iron Oxide Nanoparticles MTT assay 030212 general & internal medicine Cytotoxicity Iron oxide nanoparticles 0105 earth and related environmental sciences General Environmental Science |
| Zdroj: | Environmental Research. 201:111585 |
| ISSN: | 0013-9351 |
| DOI: | 10.1016/j.envres.2021.111585 |
| Popis: | Iron oxide nanoparticles synthesis is an expanding area of research due of their magnetic properties and possible applications in several novel technologies. FeONPs are indispensable in the biomedical field for diagnosis, treatments and drug delivery and in bioremediation applications. The synthesis route of nanoparticles is a major concern because biological methods are eco-friendly, and chemical methods are considered toxic. The objective of this study is to synthesize FeONPs by two different methods and to compare their properties and efficiency in applications. FeONPs were synthesized and characterized by microscopic and various spectroscopic techniques. The synthesized FeONPs were screened for their cytotoxic activity on PBMCs using MTT assay and found to exhibit good biocompatibility. Moreover, the GS FeONPs exhibited potential antibacterial activities and meanwhile showed less toxicity in brine shrimp lethality assay. Hence, these nanoparticles are biocompatible, environmentally safe and can be utilized in many medical applications. |
| Databáze: | OpenAIRE |
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