Total Synthesis and Stereochemistry Assignment of Nucleoside Antibiotic A-94964

Autor:	Xiaofei Shao, Chang Zheng, Peng Xu, Taro Shiraishi, Tomohisa Kuzuyama, Antonio Molinaro, Alba Silipo, Biao Yu
Přispěvatelé:	Shao, X., Zheng, C., Xu, P., Shiraishi, T., Kuzuyama, T., Molinaro, A., Silipo, A., Yu, B.
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Magnetic Resonance Spectroscopy Nucleoside Antibiotic Nucleosides Stereoisomerism General Medicine General Chemistry A-94964 Disaccharides Phosphodiester Catalysis Anti-Bacterial Agents Total Synthesis Pyrimidine Nucleotides Octuronic Acid Uridine
Popis:	A collective total synthesis of eight diastereoisomers associated with NMR analysis leads to a full stereochemistry assignment of the structurally unique nucleoside antibiotic A-94964, which features an octuronic acid uridine core decorated with an α-D-mannopyranosyl residue and an α-D-N-acylglucosaminopyranosyl residue via a phosphodiester bridge.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac0708d248ae0dca9b1a47b2583cea6 http://hdl.handle.net/11588/880157 Zobrazit plný text záznamu