Ocular manifestations of
| Autor: | Forum Kapadi, M Manjunath, Girish Baliga, Manohar Babu Balasundaram |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Male
Scrub typhus Rickettsiosis Eye Eye Infections Bacterial 0302 clinical medicine lcsh:Ophthalmology Fluorescein Angiography Child biology Middle Aged Antibodies Bacterial Weil–Felix test Anti-Bacterial Agents Drug Combinations Doxycycline Original Article Female Rickettsia conorii Tomography Optical Coherence Vasculitis Adult medicine.medical_specialty Adolescent 030231 tropical medicine Retinitis India Q fever Enzyme-Linked Immunosorbent Assay Boutonneuse Fever 03 medical and health sciences Young Adult multifocal retinitis medicine Humans Glucocorticoids Retrospective Studies business.industry medicine.disease biology.organism_classification bacterial infections and mycoses Dermatology Spotted fever Ophthalmology lcsh:RE1-994 030221 ophthalmology & optometry Commentary business Typhus |
| Zdroj: | Indian Journal of Ophthalmology Indian Journal of Ophthalmology, Vol 66, Iss 12, Pp 1840-1844 (2018) |
| ISSN: | 1998-3689 |
| Popis: | Purpose: Among the major groups of rickettsiosis, the commonly reported diseases in India are: (a) Typhus group induced—scrub typhus, murine flea-borne typhus; (b) Spotted fever group induced—Indian tick typhus; and (c) Q fever. Though many scrub typhus outbreaks have been reported from India, only one outbreak of spotted fever—serologically proven Indian tick typhus (Rickettsia conorii)—has been reported. We report for the first time ocular manifestations of serologically proven R. conorii infection in a cluster of patients. Methods: In this retrospective study, case records patients with serologically proven Indian tick typhus (Rickettsia conorii) were reviewed for clinical manifestations and treatment outcomes. Results: In the months of February to April 2016, a cluster of 12 patients (23 eyes) visited us with defective vision. Examination showed multifocal retinitis; mostly bilateral; patients had a history of fever approximately 4 weeks prior to onset of symptoms. After excluding other causes of multifocal retinitis, a diagnosis of rickettsial retinitis was made after Weil–Felix test (WFT) was significantly positive, and enzyme-linked immunosorbent assay was positive for R. conorii. Course of the disease, visual outcome, and investigations are discussed. Doxycycline along with oral corticosteroids was effective in treating the condition. Conclusion: Systematic fundus examination should be part of the routine evaluation of any patient who presents with fever and/or skin rash living in or returning from a specific endemic area. Clinical clues to diagnosing ocular rickettsiosis could be multifocal retinitis predominantly involving the posterior pole and macular involvement in the form of serous macular detachment or macular hard exudates. A positive WFT still serves as a useful and cheap diagnostic tool for laboratory diagnosis of rickettsial disease. Doxycycline along with oral corticosteroids was effective in treating the condition. |
| Databáze: | OpenAIRE |
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