Anatomic vs. Acquired Image Frame Discordance in Spectral Domain Optical Coherence Tomography Minimum Rim Measurements
| Autor: | Shaban Demirel, Hongli Yang, Brad Fortune, Ruojin Ren, Stuart K. Gardiner, Claude F. Burgoyne, Christy Hardin, Luke Reyes, Juan Reynaud, Lin He |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Fovea Centralis Eye Diseases Ocular Anatomy Optic Disk Optic disk lcsh:Medicine Glaucoma Spectral domain Nuclear magnetic resonance Optical coherence tomography Ocular System medicine Medicine and Health Sciences Humans Longitudinal Studies lcsh:Science Aged Physics Aged 80 and over Multidisciplinary medicine.diagnostic_test lcsh:R Fovea centralis Biology and Life Sciences Anatomy Organ Size Middle Aged medicine.disease Image frame Ophthalmology medicine.anatomical_structure Neurology Optic nerve Neuro-Ophthalmology lcsh:Q Female Tomography Tomography Optical Coherence Research Article |
| Zdroj: | PLoS ONE PLoS ONE, Vol 9, Iss 3, p e92225 (2014) |
| ISSN: | 1932-6203 |
| Popis: | Purpose To quantify the effects of using the fovea to Bruch's membrane opening (FoBMO) axis as the nasal-temporal midline for 30° sectoral (clock-hour) spectral domain optical coherence tomography (SDOCT) optic nerve head (ONH) minimum rim width (MRW) and area (MRA) calculations. Methods The internal limiting membrane and BMO were delineated within 24 radial ONH B-scans in 222 eyes of 222 participants with ocular hypertension and glaucoma. For each eye the fovea was marked within the infrared reflectance image, the FoBMO angle (θ) relative to the acquired image frame (AIF) horizontal was calculated, the ONH was divided into 30°sectors using a FoBMO or AIF nasal/temporal axis, and SDOCT MRW and MRA were quantified within each FoBMO vs. AIF sector. For each sector, focal rim loss was calculated as the MRW and MRA gradients (i.e. the difference between the value for that sector and the one clockwise to it divided by 30°). Sectoral FoBMO vs. AIF discordance was calculated as the difference between the FoBMO and AIF values for each sector. Generalized estimating equations were used to predict the eyes and sectors of maximum FoBMO vs. AIF discordance. Results The mean FoBMO angle was −6.6±4.2° (range: −17° to +7°). FoBMO vs. AIF discordance in sectoral mean MRW and MRA was significant for 7 of 12 and 6 of 12 sectors, respectively (p |
| Databáze: | OpenAIRE |
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