High burden of the metabolic syndrome and its component disorders in South Africans with psoriasis

Autor: Mohammed Tikly, Lushen Pillay, Nasrin Goolam Mahyoodeen, Nigel J. Crowther, Tracy Snyman
Rok vydání: 2018
Předmět:
Zdroj: International Journal of Dermatology. 58:557-562
ISSN: 1365-4632
0011-9059
Popis: BACKGROUND Psoriasis is associated with cardiometabolic diseases (CMDs) in Caucasians, but no data is available from sub-Saharan populations on either CMD prevalence or psoriasis risk factors. Our aim was to investigate the prevalence of CMDs in a predominantly non-Caucasian cohort of South Africans with psoriasis and to determine the principal risk factors associated with psoriasis. METHODS This was a cross-sectional case-control study of adult psoriasis patients (n = 103) and controls (n = 98), comparing sociodemographic, anthropometric, clinical, and biochemical characteristics. The groups were matched for gender, ethnicity, and body mass index (BMI). RESULTS The prevalence of metabolic syndrome (MetS) (52.4% vs. 33.7%; P = 0.007), type 2 diabetes (T2D) (25.2% vs. 4.1%; P
Databáze: OpenAIRE