Evaluation of cytology and histopathology for the diagnosis of feline orbital neoplasia: 81 cases (2004‐2019) and review of the literature
| Autor: | Nicholas A. Robinson, Stephanie A. Pumphrey, Daniela Isaza, Stefano Pizzirani |
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| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Lymphoma 040301 veterinary sciences Cytological Techniques Cat Diseases 0403 veterinary science 03 medical and health sciences 0302 clinical medicine Predictive Value of Tests Cytology Animals Medicine Medical diagnosis CATS General Veterinary business.industry Records 04 agricultural and veterinary sciences medicine.disease Pedigree Massachusetts Carcinoma Squamous Cell Cats 030221 ophthalmology & optometry Orbital Neoplasms Population study Female Histopathology Sarcoma Radiology Sample collection business |
| Zdroj: | Veterinary Ophthalmology. 23:682-689 |
| ISSN: | 1463-5224 1463-5216 |
| DOI: | 10.1111/vop.12776 |
| Popis: | Objective To provide an updated overview of feline orbital neoplasia, to compare diagnostic utility of cytology and histopathology, and to evaluate minimally invasive sampling modalities. Procedures A medical records search was performed to identify cats with orbital neoplasia. Data were collected regarding signalment, diagnosis, vision status, imaging modalities, and sample collection methods. A reference population with orbital neoplasia was also identified via literature search for comparison with regard to final diagnosis. Results Eighty-one cats met selection criteria and 140 cases were identified in the literature. In the study and reference populations, respectively, diagnoses were grouped as follows: round cell tumors 47% and 24%, epithelial tumors 38% and 40%, mesenchymal tumors 14% and 34%, and neurologic origin tumors 1% and 2%. The most common diagnoses in both groups were lymphoma and squamous cell carcinoma (SCC). Feline restrictive orbital myofibroblastic sarcoma (FROMS) was common in the reference population but not diagnosed in the study population. Cytology results were available for 41 cats; histopathology results were available for 65 cats. Both cytology and histopathology results were available for 25 cats, in 44% of which cytologic results were overturned. No significant complications were associated with any sampling method. Lack of cats with multiple samples available for histopathology limited comparison between tissue sampling methods. Conclusions Orbital neoplasia is common in cats, with round cell and epithelial tumors diagnosed most commonly in the study population. Histopathology is superior to cytology in providing a definitive diagnosis. Minimally invasive tissue biopsy techniques appear to be safe and effective. |
| Databáze: | OpenAIRE |
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