The effect of lead (Pb) exposure and iron (Fe) deficiency on intestinal lactobacilli, E. coli and yeast: A study in experimental rats
| Autor: | Sarath Babu Srivalliputturu, Dinesh Kumar Bharatraj, Yathapu Srinivasa Reddy |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Male
0301 basic medicine medicine.medical_specialty food.ingredient Original Oral lead (Pb) exposure Iron Population Weanling Rats Sprague-Dawley Feces Hemoglobins Random Allocation 03 medical and health sciences food Dietary iron (Fe) Yeasts Internal medicine Escherichia coli Organometallic Compounds medicine Iron deficient Animals Agar education Analysis of Variance education.field_of_study 030109 nutrition & dietetics medicine.diagnostic_test Chemistry Body Weight E. coli Public Health Environmental and Occupational Health Porphobilinogen Synthase Iron Deficiencies Yeast Animals Suckling Diet Rats Lactobacillus 030104 developmental biology Endocrinology Lactobacilli Dehydratase Serum iron Female |
| Zdroj: | Journal of Occupational Health |
| ISSN: | 1348-9585 1341-9145 |
| Popis: | Objective: The current study investigated the additive effect of oral lead (Pb) exposure and dietary iron (Fe) deficiency on intestinal lactobacilli, E. coli, and yeast in SD rats. Methods: Weanling rats were fed on control diet (CD) or iron deficient diet (ID) for 4 weeks, followed by oral Pb exposure for another 4 weeks. Lead exposure was withdrawn for 2 weeks, and then resumed after 2 weeks. Blood samples were collected to determine haemoglobin (Hb), serum iron, blood Pb and δ-Aminolevulenic acid dehydratase (ALAD) activity. Fecal samples were collected to enumerate the lactobacilli, E. coli and yeast population on selective agar media and determine Pb levels. Results: Hb and serum Fe levels decreased significantly in iron deficient rats. Pb exposed rats had a significant increase in blood Pb levels and decreased ALAD activity. The lactobacilli population was significantly decreased (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text