Testosterone free index correlates best with dehydroepiandrosterone sulfate
| Autor: | Ray V. Haning, Wolfram E. Nolten, Ian H. Carlson, Sander S. Shapiro |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
endocrine system
medicine.medical_specialty Menotropins Population Estriol glucuronide Luteal Phase chemistry.chemical_compound Dehydroepiandrosterone sulfate Internal medicine medicine Humans Testosterone Androstenedione education Amenorrhea education.field_of_study Obstetrics and Gynecology Dehydroepiandrosterone Prolactin Endocrinology Reproductive Medicine chemistry Female Menotropin Luteinizing hormone Infertility Female hormones hormone substitutes and hormone antagonists Polycystic Ovary Syndrome |
| Zdroj: | Fertility and Sterility. 36:757-765 |
| ISSN: | 0015-0282 |
| DOI: | 10.1016/s0015-0282(16)45922-4 |
| Popis: | Correlation coefficients for dehydroepiandrosterone sulfate (DHEAS) were determined in women on menotropin. DHEAS was significantly correlated with testosterone free index (TFI), 0.78**; percentage free testosterone (%FT), 0.66**; androstenedione (delta 4A), 0.66*; luteinizing hormone (LH), 0.55**; LH/follicle-stimulating hormone (FSH) ratio, 0.55**; 17-OH-progesterone (17-P), 0.55**; testosterone (T), 0.53**; weight (WT), 0.40**, urinary estriol glucuronide (E3G), 0.33*; and free cortisol index (FFI), 0.32*, with 43 df but not with prolactin (PRL), 0.25. Normal male DHEAS (3.5 +/- 1.2, 25) (microgram/ml; mean +/- standard deviation, n) was higher than normal female DHEAS (2.4 +/- 1.1, 27), P less than 0.01 and DHEAS in women on oral contraceptives (1.9 +/- 1.1, 17) was slightly lower than in normal females, P greater than 0.2. In the combined population (male, female, and females on oral contraceptives) DHEAS was correlated with TFI (0.56**), T (0.54**), %FT (0.52**), delta 4A (0.40**), and age (-0.40**) with 66 df and 17-P (0.30*) with 54 df. TFI appears to be one determinant of plasma DHEAS, **P less than 0.01. *P less than 0.05. |
| Databáze: | OpenAIRE |
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