Digestibility, toxicity and metabolic effects of rapeseed and sunflower protein hydrolysates in mice
| Autor: | Carlo Pinna, Monica Grandi, Luisa Ugolini, Emanuele Conte, Donatella Canistro, Luca Lazzeri, Giacomo Biagi, Silvia Cirillo, Fabio Vivarelli, Andrea Sapone, Ippazio Cosimo Antonazzo, Susanna Cinti |
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| Přispěvatelé: | Canistro, D., Vivarelli, F., Ugolini, L., Pinna, C., Grandi, M., Antonazzo, I.C., Cirillo, S., Sapone, A., Cinti, S., Lazzeri, L., Conte, E., Biagi, G, Canistro, D, Vivarelli, F, Ugolini, L, Pinna, C, Grandi, M, Antonazzo, I, Cirillo, S, Sapone, A, Cinti, S, Lazzeri, L, Conte, E |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Rapeseed sunflower 040301 veterinary sciences hydrolysate rapeseed Biology Hydrolysate 0403 veterinary science 03 medical and health sciences Mice Enzymatic hydrolysis study Palatability lcsh:SF1-1100 chemistry.chemical_classification toxicity 04 agricultural and veterinary sciences Metabolism Sunflower 030104 developmental biology Enzyme Biochemistry chemistry Toxicity Animal Science and Zoology lcsh:Animal culture protein |
| Zdroj: | Italian Journal of Animal Science, Vol 16, Iss 3, Pp 462-473 (2017) |
| Popis: | The digestibility (in vitro), toxicity and metabolic effects of rapeseed (RPH) and sunflower (SPH) protein hydrolysates have been evaluated in a murine animal model. The enzyme AlcalaseVR was employed to obtain a mild enzymatic hydrolysis of rapeseed and sunflower defatted seed meals (DSM) protein isolates. Both hydrolysates showed higher in vitro digestibility than the respective DSM, presumably as a consequence of the hydrolysis process that they had undergone. In vivo, RPH and SPH were well tolerated. Body and organ weights, biochemical blood parameters from treated male mice were comparable to controls. Food intake was regular in RPH and SPH animals, suggesting a good palatability of the hydrolysates. Not relevant perturbations of the principal hepatic and renal drug metabolism enzymes were observed in RPH or SPH mice. In conclusion, protein hydrolysates from sunflower and rapeseed DSM did not determine relevant toxicological effects; therefore, they could be considered as alternative protein sources and/or food ingredients. |
| Databáze: | OpenAIRE |
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