A case of primary tularemic pneumonia presenting with necrotizing mediastinal and hilar lymph nodes
Autor: | Alois Kreuzer, Otto C. Burghuber, Anna Csokay, Hubert Koller, Arschang Valipour, Wolfgang Kössler |
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Rok vydání: | 2003 |
Předmět: |
Male
Pathology medicine.medical_specialty Disease Tularemia Diagnosis Differential Necrosis Bronchoscopy Hilar lymph nodes Biopsy Pneumonia Bacterial Medicine Humans Francisella tularensis Lymphatic Diseases Aged medicine.diagnostic_test business.industry Biopsy Needle Mediastinum General Medicine bacterial infections and mycoses medicine.disease Agricultural Workers' Diseases Pneumonia medicine.anatomical_structure Austria Immunology Lymph Nodes business |
Zdroj: | Wiener klinische Wochenschrift. 115(5-6) |
ISSN: | 0043-5325 |
Popis: | Tularemia is an unusual disease caused by the gram-negative coccobacillus Francisella tularensis. The clinical features of the disease depend on the route of inoculation. Ulceroglandular and typhoidal forms have been recognized as occurring in tularemia, however primary or secondary pneumonic infections have also been reported. Symptoms, laboratory markers and radiological features are non-specific in tularemic pneumonia. Diagnosis is made on clinical grounds and evidence of elevated agglutinating antibodies to F. tularensis (1:128). We report a case of primary tularemic pneumonia presenting with pulmonary infiltrates and necrotizing mediastinal and hilar lymph nodes in an otherwise healthy subject from a non-endemic area. Diagnosis of tularemia was obtained serologically, and antibiotic therapy with doxycycline and streptomycin resolved symptoms and radiological abnormalities. We suggest that tularemia should be considered in the differential diagnosis of pneumonia with mediastinal and/or hilar lymphadenopathy. |
Databáze: | OpenAIRE |
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