Regular Exercise, Quality of Life, and Mobility in Parkinson’s Disease: A Longitudinal Analysis of National Parkinson Foundation Quality Improvement Initiative Data
| Autor: | Kan Li, Tanya Simuni, Miriam R. Rafferty, Sheng Luo, Thomas L. Davis, Fernando Cubillos, Mark Guttman, Connie Marras, Peter Schmidt |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Parkinson's disease Quality management medicine.medical_treatment Disease Article 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine Physical medicine and rehabilitation Quality of life Regular exercise Outcome Assessment Health Care Medicine Humans 030212 general & internal medicine Longitudinal Studies Mobility Limitation Exercise Aged Aged 80 and over Rehabilitation Exercise intervention business.industry Parkinson Disease Middle Aged medicine.disease humanities Physical therapy Quality of Life Observational study Female Neurology (clinical) business human activities 030217 neurology & neurosurgery |
| Popis: | BACKGROUND Research-based exercise interventions improve health-related quality of life (HRQL) and mobility in people with Parkinson's disease (PD). OBJECTIVE To examine whether exercise habits were associated with changes in HRQL and mobility over two years. METHODS We identified a cohort of National Parkinson Foundation Quality Improvement Initiative (NPF-QII) participants with three visits. HRQL and mobility were measured with the Parkinson's Disease Questionnaire (PDQ-39) and Timed Up and Go (TUG). We compared self-reported regular exercisers (≥2.5 hours/week) with people who did not exercise 2.5 hours/week. Then we quantified changes in HRQL and mobility associated with 30-minute increases in exercise, across PD severity, using mixed effects regression models. RESULTS Participants with three observational study visits (n = 3408) were younger, with milder PD, than participants with fewer visits. After 2 years, consistent exercisers and people who started to exercise regularly after their baseline visit had smaller declines in HRQL and mobility than non-exercisers (p |
| Databáze: | OpenAIRE |
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