Local delivery of heparin with balloon angioplasty: results of a prospective randomized trial
| Autor: | Blayne A. Standage, Philip D. Feliciano, Robert C. Sheley, John W. Ragsdale, Stephen F. Quinn, Earl S. Schuman |
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| Rok vydání: | 1996 |
| Předmět: |
Male
medicine.medical_specialty Time Factors medicine.medical_treatment Population Balloon Arteriovenous Shunt Surgical Renal Dialysis Angioplasty medicine Humans Radiology Nuclear Medicine and imaging Life Tables Prospective Studies education Vein Polytetrafluoroethylene Dialysis Vascular Patency education.field_of_study business.industry Heparin Balloon catheter Graft Occlusion Vascular Anticoagulants Middle Aged Surgery medicine.anatomical_structure Female Hemodialysis Cardiology and Cardiovascular Medicine business Angioplasty Balloon medicine.drug |
| Zdroj: | Journal of vascular and interventional radiology : JVIR. 7(6) |
| ISSN: | 1051-0443 |
| Popis: | Purpose To evaluate the effectiveness of local delivery of heparin via hydrogel-coated balloons in the treatment of vascular stenoses associated with hemodialysis access. Materials and Methods This was a randomized, prospective trial comparing treatment with hydrogel-coated balloon catheters delivered with heparin coating ( n = 33) and without ( n = 26). All patients were undergoing hemodialysis, and all stenoses involved the venous anastomosis of a dialysis graft or a native vein. The heparin-treated balloons were soaked in concentrated heparin and delivered in a protected manner to help prevent washout of heparin. Results The mean primary patencies were 143 days with heparin treatment and 214 days without heparin ( P = .174). The mean assisted primary patencies were 165 days with heparin and 194 days without ( P = .315). The mean secondary patencies were 351 days with heparin and 384 without ( P = .81). Conclusion In this population with this technique, the treatment outcome of venous outflow stenosis in patients with dialysis grafts is not improved with local delivery of heparin. |
| Databáze: | OpenAIRE |
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