Toward a Novel Medical Device Based on Chromatic Pupillometry for Screening and Monitoring of Inherited Ocular Disease: A Pilot Study

Autor: Paolo Nucci, Edoardo Villani, Maria Concetta Ferraro, Ernesto Iadanza, Paolo Melillo, Antonella De Benedictis, Francesco Testa, Francesca Simonelli, Monica Gherardelli, Sandro Banfi
Přispěvatelé: Melillo, Paolo, de Benedictis, Antonella, Villani, Edoardo, Ferraro, Maria Concetta, Iadanza, Ernesto, Gherardelli, Monica, Testa, Francesco, Banfi, Sandro, Nucci, Paolo, Simonelli, Francesca
Rok vydání: 2018
Předmět:
Zdroj: IFMBE Proceedings ISBN: 9789811090226
DOI: 10.1007/978-981-10-9023-3_70
Popis: Chromatic pupillometry is a relatively novel research tool for retinal function evaluation and may be an appropriate and easier way to diagnose and monitor inherited retinal diseases in paediatric population. Nevertheless, although the method is clinically feasible in paediatric populations, as shown by several non-ocular studies, only few studies, on a small size sample of paediatric subjects, are available. To the best of the authors’ knowledge, no medical device based on chromatic pupillometry was CE-marked for diagnosis and/or monitoring of these conditions. Therefore, we designed a pilot study in order to evaluate clinical feasibility, reliability and utility of chromatic pupillometry. The study sample consists of sixty patients, affected by inherited ocular diseases. A pupillometric system, including definition of pupillometric protocols, have been set up. In the current paper, we present the comparison between the measurements obtained in one patient affected by Retinitis Pigmentosa and a healthy age-matched control in order to disclose differences in chromatic pupillometry parameters between case and control.
Databáze: OpenAIRE