Comparison of a receptor binding assay with a radioimmunoassay for measuring human epidermal growth factor-urogastrone in urine
| Autor: | S. I. Lamberg, Ebba Nexø, Morley D. Hollenberg |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Adult
Male medicine.medical_specialty Urinary system Clinical Biochemistry Radioimmunoassay Urine Biology Immobilization Radioligand Assay Epidermal growth factor Internal medicine Psoriasis medicine Humans Receptor Aged Epidermal Growth Factor Human epidermal growth factor Binding protein General Medicine Middle Aged medicine.disease Endocrinology Evaluation Studies as Topic Burns |
| Zdroj: | Scandinavian Journal of Clinical and Laboratory Investigation. 41:577-582 |
| ISSN: | 1502-7686 0036-5513 |
| DOI: | 10.3109/00365518109090501 |
| Popis: | A radioreceptor assay for human epidermal growth factor-urogastrone (EGF-URO) employing mouse EGF-URO as tracer and calibration standards and human placental receptor as binding protein is compared with a radioimmunoassay for human EGF-URO. Results employing the receptor assay indicated similar values for urinary concentrations (1-16 nmol/l) for healthy control subjects and for patients with psoriasis. Lower values were obtained for bed-ridden patients with burns or patients recovering from orthopaedic surgery. The results obtained by radioimmunoassay were somewhat higher and correlated poorly (r = 0.5) with those obtained with the radioreceptor assay. The reason for this discrepancy is discussed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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