A Case of Metastatic Low-Grade Endometrial Stromal Sarcoma Treated with Letrozole after Ovarian Ablation by Radiotherapy
| Autor: | Seong Yoon Yi, Kyung Ho Yang, Jung A. Shin, Hae Won Jung, Sunhee Chang, Ji Yeon Park, Hye Ran Lee, Joo Hyuk Jung |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Ablation Techniques
Cancer Research medicine.medical_specialty medicine.medical_treatment Sarcoma Endometrial Stromal Urology Endometriosis Ovarian Ablation Antineoplastic Agents Case Report Follicle-stimulating hormone Nitriles medicine Humans Adenomyosis Endometrial stromal sarcoma Gynecology Hysterectomy Radiotherapy business.industry Letrozole Middle Aged Triazoles medicine.disease Endometrial Neoplasms Radiation therapy Oncology Chemotherapy Adjuvant Endometrial stromal tumors Ovarian ablation Female business medicine.drug |
| Zdroj: | Cancer Research and Treatment : Official Journal of Korean Cancer Association |
| ISSN: | 2005-9256 |
| Popis: | A 50-year-old woman was admitted to our hospital due to multiple lung nodules detected incidentally on a chest X-ray. A video-assisted thoracoscopic lung biopsy revealed low-grade endometrial stromal sarcoma (LG-ESS). She had undergone a simple hysterectomy 1 year earlier owing to a diagnosis of adenomyosis. A review of her previous hysterectomy specimen showed not endometriosis but LG-ESS. According to the patient’s levels of serum follicle stimulating hormone and estradiol, she was in the premenopausal state with retained and normally functioning ovaries. She then underwent ovarian ablation by radiotherapy, after which she was administered 2.5 mg of letrozole once per day. Three months later, the size of the metastatic nodules in both lungs had decreased. The patient was followed up for 24 months while continuing on letrozole, and maintained a partial remission. We report herein on a case of metastatic LG-ESS treated with letrozole after ovarian ablation by radiotherapy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|