In Vivo Evaluation of Biocompatibility of Three Biomaterials Used in Endodontics for Prosthetic Purposes in Complex Rehabilitation Treatment
Autor: | Yllka Decolli, Eusebiu Viorel Sindilar, Eugen Mihalas, Bogdan Petru Bulancea, Liana Aminov, Laurian Francu, Cristina Antohi, Ovidiu Stamatin, Aurelian Sorin Pasca, Laura Elisabeta Checherita, Lupu Iulian Costin |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Mineral trioxide aggregate
medicine.medical_specialty Technology Subcutaneous connective tissue Biocompatibility QH301-705.5 Root canal QC1-999 Dentistry subcutaneous implantation 010402 general chemistry 01 natural sciences 03 medical and health sciences BioAggregate 0302 clinical medicine biocompatibility medicine General Materials Science Biology (General) Instrumentation QD1-999 Fluid Flow and Transfer Processes business.industry Process Chemistry and Technology Physics General Engineering Biomaterial 030206 dentistry Endodontics Engineering (General). Civil engineering (General) oral rehabilitation homeostasis 0104 chemical sciences Computer Science Applications Cementogenesis Chemistry medicine.anatomical_structure prosthetic restoration TA1-2040 business biomaterials |
Zdroj: | Applied Sciences Volume 11 Issue 14 Applied Sciences, Vol 11, Iss 6519, p 6519 (2021) |
ISSN: | 2076-3417 |
DOI: | 10.3390/app11146519 |
Popis: | The ideal biomaterial used in endodontics in the process of sealing the radicular canals should possess a group of qualities for a predictable outcome: biocompatibility, initiation of ontogenesis and cementogenesis, ease of handling, sufficient manipulation time, and convenient price. For a perfect sealing, the root canal treatment can be followed by prosthetic restoration. This study of biocompatibility aims to determine the quantification of the local reaction following the implantation of three biomaterials in the rabbit subcutaneous connective tissue. The used biomaterials with particular reparative properties are: MTA (Mineral Trioxide Aggregate, Dentsply, Tulsa Dental, Johnson City, TN, USA), Sealapex (Kerr, Switzerland), and DiaRoot BioAggregate (Innovative BioCaramix Inc, Vancouver, BC, Canada). The first two biomaterials (MTA, Sealapex) are already being used in endodontic treatments, and the latter was newly introduced during the concrete development of the study. This is an experimental study focused on qualitative and quantitative analysis based on histopathological examination and underlined by the positive result of the study undertaken of the applicability of oral rehabilitation treatments, increasing patients’ quality of life by a significant proportion of 95%, and generating optimal functionality of the stomatognathic system with prosthetic devices as well as accomplishing the objectives of homeostasis. |
Databáze: | OpenAIRE |
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