Parsing the clinical phenotype of depression: the need to integrate brief depressive episodes

Autor:	Wulf Rössler, Lukas Pezawas, Dominique Eich, Alex Gamma, Vladeta Ajdacic-Gross, C. Altamura, Jules Angst
Přispěvatelé:	University of Zurich, Angst, J
Rok vydání:	2007
Předmět:	Questionnaires Adult Male Periodicity medicine.medical_specialty Time Factors 610 Medicine & health 10056 Clinic for Clinical and Social Psychiatry Zurich West (former) Diagnosis Differential 2738 Psychiatry and Mental Health Recurrent brief depression Major/*diagnosis/epidemiology/*psychology Switzerland/epidemiology Surveys and Questionnaires Diagnosis Prevalence medicine Humans Prospective Studies Family history Psychiatry Depression (differential diagnoses) Depressive Disorder Depressive Disorder Major Suicide attempt Phenotype Incidence medicine.disease Comorbidity Psychiatry and Mental health Distress Mood 10054 Clinic for Psychiatry Psychotherapy and Psychosomatics Differential Anxiety Female medicine.symptom Psychology Switzerland Clinical psychology
Zdroj:	Acta Psychiatrica Scandinavica. 115:221-228
ISSN:	1600-0447 0001-690X
DOI:	10.1111/j.1600-0447.2006.00893.x
Popis:	OBJECTIVE: To expand the concept of recurrent brief depression (RBD) to brief depression (BD) and to test its clinical relevance. METHOD: Subjects (N = 591) were studied prospectively six times from ages 20/21 to 40/41 years. RBD was defined according to DSM-IV as episodes under 2 weeks with about monthly recurrence and work impairment. BD embraces RBD and brief depressive episodes with a frequency of 1-11 per year. RESULTS: Pure BD and pure major depressive episodes (MDE) did not differ in treatment rates, family history of mood and anxiety disorders or comorbidity with bipolar spectrum and anxiety disorders but they differed in work impairment, suicide attempt rates and distress self-ratings. The combination of BD + MDE identified a very severe group of MDE, comparable with combined depression (MDE + RBD) and double depression (MDE + dysthymia). CONCLUSION: Our data argue for the use of BD as a diagnostic specifier for severe MDE. RBD remains an important independent subgroup.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a83fe8f6a33f44c26c029d78923985d https://doi.org/10.1111/j.1600-0447.2006.00893.x Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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