Particle Design and Inhalation Delivery of Iodine for Upper Respiratory Tract Infection Therapy

Autor:	Kaikai, Zhang, Xiaohong, Ren, Jiacai, Chen, Caifen, Wang, Siyu, He, Xiaojin, Chen, Ting, Xiong, Jiawen, Su, Shujun, Wang, Weifeng, Zhu, Jiwen, Zhang, Li, Wu
Rok vydání:	2022
Předmět:	Cyclodextrins Ecology Interleukin-6 Tumor Necrosis Factor-alpha Pharmaceutical Science Pneumonia General Medicine Aquatic Science Rats Administration Inhalation Drug Discovery Animals Particle Size Agronomy and Crop Science Ecology Evolution Behavior and Systematics Iodine
Zdroj:	AAPS PharmSciTech. 23
ISSN:	1530-9932
Popis:	Diseases caused by upper respiratory tract (URT) and pulmonary infections have been a serious threat to human health for millennia and lack of targeted effective therapeutic techniques. In this study, two kinds of cyclodextrin particles with typical particle shapes of nanocubes and microbars were synthesized through a facile process. Subsequently, the particles were used as carriers for loading and stabilizing iodine and characterizations were performed to demonstrate the loading mechanism. Next-generation impactor (NGI) experiments showed that iodine-loaded microbars (I
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a83449ca1dab62c6042d1a9dcad0fa1 https://doi.org/10.1208/s12249-022-02277-x Zobrazit plný text záznamu Full text from SpringerLink