Consensus on the Treatment and Follow-Up for Metastatic Castration-Resistant Prostate Cancer: A Report From the First Global Prostate Cancer Consensus Conference for Developing Countries (PCCCDC)
| Autor: | Aldo Lourenço Abbade Dettino, Fernando C. Maluf, Ariel Galapo Kann, João Francisco Navarro Reolon, Juan Jose Zarbá, Igor Alexandre Protzner Morbeck, Karine Martins da Trindade, Ana Paula Garcia Cardoso, José Augusto Rinck, Diego Emilio Lopera Cortés, André Seeke Sasse, Juan Pablo Sade, Adriano Gonçalves E Silva, Andrey Soares, Silke Gillessen, L. Costa, Manuel Caitano Maia, Denis Leonardo Fontes Jardim, Mariana Bruno Siqueira, Daniel Herchenhorn, Lucas V. dos Santos, Felipe Moraes Toledo Pereira, Fábio Roberto Kater |
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| Rok vydání: | 2021 |
| Předmět: |
Male
Oncology Cancer Research medicine.medical_specialty 030232 urology & nephrology MEDLINE Developing country Docetaxel Castration resistant Special Series: Genitourinary Malignancies in LMICs 03 medical and health sciences Prostate cancer 0302 clinical medicine Internal medicine Humans Medicine Developing Countries business.industry Consensus conference Androgen Antagonists medicine.disease SPECIAL ARTICLES Prostatic Neoplasms Castration-Resistant 030220 oncology & carcinogenesis business Follow-Up Studies |
| Zdroj: | JCO Global Oncology |
| ISSN: | 2687-8941 |
| DOI: | 10.1200/go.20.00511 |
| Popis: | PURPOSE To present a summary of the recommendations for the treatment and follow-up for metastatic castration-resistant prostate cancer (mCRPC) as acquired through a questionnaire administered to 99 physicians working in the field of prostate cancer in developing countries who attended the Prostate Cancer Consensus Conference for Developing Countries. METHODS A total of 106 questions out of more than 300 questions addressed the use of imaging in staging mCRPC, treatment recommendations across availability and response to prior drug treatments, appropriate drug treatments, and follow-up, and those same scenarios when limited resources needed to be considered. Responses were compiled and the percentages were presented by clinicians to support each response. Most questions had five to seven relevant options for response including abstain and/or unqualified to answer, or in the case of yes or no questions, the option to abstain was offered. RESULTS Most of the recommendations from this panel were in line with prior consensus, including the preference of a new antiandrogen for first-line therapy of mCRPC. Important aspects highlighted in the scenario of limited resources included the option of docetaxel as treatment preference as first-line treatment in several scenarios, docetaxel retreatment, consideration for reduced doses of abiraterone, and alternative schedules of an osteoclast-targeted therapy. CONCLUSION There was wide-ranging consensus in the treatment for men with mCRPC in both optimal and limited resource settings. |
| Databáze: | OpenAIRE |
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